| 1. | Title of the Course | Methods in Organic Synthesis |
|---|---|---|
| 2. | Course Number | CH 843/ CH 844 |
| 3. | Status of the Course | Program Elective |
| 4. | Structure of Credits | 3-0-0-3 |
| 5. | Offered To | PhD Chemistry |
| 6. | Prerequisite | Nil |
| 7. Course Objective: To understand the role and reactivity of key reactive intermediates in organic synthesis and to understand reactivity in the absence of such intermediates | ||
| 8. Course Content: Different types of Olefination reactions (Wittig, HWE, Peterson, Julia, McMurry), Olefin Metathesis, Cross-Coupling reactions (Suzuki, Buchwald-Hartwig, Heck, Sonogashira, Negishi, Hiyama etc.), Cycloaddition reactions (Diels Alder, Dipolar, 2+2+2 etc.), Application of classical reactions in Natural and Non-natural product synthesis, Asymmetric Catalysis (Metal-chiral ligand, organocatalysis), Synergistic Catalysis, C-H Functionalization Methods, Modern photochemical methods | ||
| 9. Text book(s): 1. F. A. Carey and R. A. Sundberg, Advanced Organic Chemistry, Part A & B: Reactions and Synthesis, 5th edition, Springer, New York, 2007 2. W. Carruthers and I. Coldham, Modern methods of Organic Synthesis, First South Asian Edition 2005, Cambridge University Press. |
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| 10. Reference(s): 1. J. March and M. B. Smith, March’s Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 6th Edition, Wiley, 2007. |
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