Dr. Mantu Santra

Assistant Professor






Areas of Research
Theoretical and computational Biophysical Chemistry, Structure and dynamics of fluids, Phase transition and polymorphism, Statistical Mechanics, Mathematical modeling in systems biology.
Educational Qualifications

  • Ph.D., Aug 2008 - Mar 2013, Indian Institute of Science, Bangalore
  • M. Sc. Chemistry, Aug 2005 - Jul 2008, Indian Institute of Science, Bangalore.
  • B. Sc. (Hons) Chemistry, Aug 2002 - Jul 2005, Ramakrishna Mission Vidyamandira, Belur, University of Calcutta.

Professional Appointments

  • Post doctoral Research Associate, S. N. Bose National Centre for Basic Sciences, Kolkata, Dec 2018 - Dec 2019.
  • Post doctoral Research Associate, Stony Brook University, New York, USA, Sep 2013 - Aug 2018.

Representative Publications
  • Proteostasis collapse is a driver of cell aging and death, M. Santra, K. A. Dill and A. M. R. de Gra?, Proc. Natl. Acad. Sci, USA 116 (44), 22173-22178 (2019)
  • Polymorph selection during crystallization of a model colloidal ?uid with a free energy landscape containing a metastable solid, M. Santra*, R. S. Singh and B. Bagchi*, Phys. Rev. E 98, 032606 (2018) (*Co-corresponding author)
  • How do chaperones protect a cell's proteins from oxidative damage? M. Santra*, K. A. Dill and A. M. R. de Gra?, Cell Systems 6, 743 (2018) (*Corresponding author)
  • Bacterial proteostasis balances energy and chaperone utilization e?ciently, M. Santra, D. W. Farrell and K. A. Dill, Proc. Natl. Acad. Sci, USA 114, E2654-E2661 (2017)
  • Nucleation of a Stable Solid from Melt in the Presence of Multiple Metastable Intermediate Phases: Wetting, Ostwald Step Rule and Vanishing Polymorphs, M. Santra, R. S. Singh and B. Bagchi, J. Phys. Chem. B 117, 13154 (2013)
  • Catalysis of tRNA-Aminoacylation: Single Turnover to Steady State Kinetics of tRNASynthetases, M. Santra and B. Bagchi, J. Phys. Chem. B. 116, 11809 (2012)
  • Gas-Liquid Nucleation in Two Dimensional System, M. Santra, S. Chakrabarty and B. Bagchi, J. Chem. Phys. 129, 234704 (2008)
    Recognition and Awards

    • DST Inspire Faculty Fellowship (2014)
    • The Toulouse Medal for best Ph.D. thesis, Solid State and Structural Chemistry Unit, Indian Institute of Science (2013).